2022 May 3;14(5):e24713. There are many limitations to these studies and their assumptions have occasionally been proven false in controlled trials, which are higher quality studies. The researchers also found that vegetarians had 22% lower risk of colorectal cancer compared to meat-eaters. The meta-analysis included prospective cohort and case-control studies analyzing the consumption of total dairy products, high-fat dairy products, low-fat dairy products, total milk, whole milk, low-fat milk, fermented dairy products, total yogurt, cultured milk or cheese. The database consulted were PubMed, Clinical Trials, and Cochrane to extract the relevant studies published till the 31stof December 2016, using inclusion and exclusion criteria according to Prisma Protocol. Can ice cream really be healthy? Long before fast food, packaged meals, and the mass-produced meat, dairy, and egg industries, colorectal cancer was actually considered rare, and it is still considered uncommon in underdeveloped, rural societies that eat leaner, healthier diets. Eight meta-analyses 23 39 showed non-significant associations between whole milk, milk, low-fat milk, skim milk, yogurt, cheese, cottage cheese or ice cream consumption and risk of pancreatic cancer. High dairy intake is associated with increased prostate cancer risk, but decreased colon cancer risk. High-fat dairy food and conjugated linoleic acid intakes in relation to colorectal cancer incidence in the Swedish Mammography Cohort. Cheese consumption was associated with the prevention of CRC, specifically proximal colon cancer. 7 In animal models, lactoferrin, a milk protein, has been shown to suppress carcinogenesis in the colon and other organs. Foods and beverages and colorectal cancer risk: a systematic review and meta-analysis of cohort studies, an update of the evidence of the WCRF-AICR Continuous Update Project. The latest WCRF/AICR Report (2017) concludes that consumption of dairy foods probably protects against colorectal cancer, and rates the level of evidence as 'strong' 1. In conclusion, high consumption of total dairy products and total milk was associated with a lower risk of developing CRC at any anatomic location, including the proximal and distal colon and the rectum. 3.Aune D, chan DS, Vieira AR, et al. Inverse associations were observed in both men and women but were restricted to colon cancer. Bookshelf For the study, Campbell's team collected data on almost 2,300 people diagnosed between 1992 and 2009 with colon cancer that had not spread beyond the colon. According to the World Cancer Research Fund International,there is strong evidence that dairy reduces the risk of developing colorectal cancer. 2022 Oct 18;14(20):4362. doi: 10.3390/nu14204362. See the 10 protein bars our dietitians and taste-testers deemed. Larsson SC et al. The https:// ensures that you are connecting to the consuming foods containing dietary fibre DECREASES the risk of colorectal cancer consuming dairy products DECREASES the risk of colorectal cancer taking calcium supplements DECREASES the risk of colorectal cancer consuming red meat INCREASES the risk of colorectal cancer consuming processed meat INCREASES the risk of colorectal cancer Cancer. 2022 Aug 27;22(1):1625. doi: 10.1186/s12889-022-14042-7. Possible protective milk components may include conjugated linoleic acid (CLA) and certain probiotic bacteria in fermented milk products (28, 29). [3] Both liver and breast cancer are among the most common types of cancer in China, accounting for around 393,000 and 368,000 new cancer cases each year respectively. Butter is a dairy product, made from cream. Disclaimer, National Library of Medicine Eur J ClinNutr2003;57:1-17. Is Butter a Dairy Product, and Does It Contain Lactose? The diagnosis of colorectal cancer is made by tissue biopsy, typically obtained during a colonoscopy. government site. Virtually all human studies on the connection between milk and cancer are observational in nature. Previous studies of the association between intake of dairy products and colorectal cancer risk have indicated an inverse association with milk, however, the evidence for cheese or other dairy products is inconsistent. The latest report fromthe World Cancer Research Fund (WCRF) and the AICR, states that consuming dairy products decreases the risk of colorectal cancer. A study using data from the Swedish Mammography Cohort has demonstrated an inverse relationship between high-fat milk products and CLA and colorectal cancer.8, Other dairy components Conjugated linoleic acid (CLA) These studies also showed a significant protective association between low-fat milk consumption and CRC (RR: 0.76; 95% CI: 0.66, 0.88), but only for colon cancer (RR: 0.73; 95% CI: 0.61, 0.87). Dairy products have been hypothesized to protect against colorectal cancer risk due to their high calcium content, which may bind proinflammatory secondary bile acids and ionized fatty acids and may reduce cell proliferation and promote cell differentiation 6., 7.. In addition to protecting against colorectal cancer, milk and other dairy products are good sources of calcium, which is necessary for bone health. If the results of a recent study hold true, you might consider. The summary RR was 0.83 (95% CI [confidence interval]: 0.78-0.88, I2=25%) per 400 g/day of total dairy products, 0.91 (95% CI: 0.85-0.94, I2=0%) per 200 g/day of milk intake and 0.96 (95% CI: 0.83-1.12, I2=28%) per 50 g/day of cheese. There is good evidence that dairy products decrease the risk of bowel cancer. The main hypothesis underlying a possible protective effect of dairy products relates to. Sign up today, and youll receive a copy of NutriNews in your inbox every month from the Dairy Farmers of Canada. Some claim that eating primarily raw foods benefits your health, but others disagree. For other types of cancer, the results are more inconsistent but generally indicate no adverse effects. However, it is better to be safe than sorry. Stomach cancer, also known as gastric cancer, is the fourth most common cancer in the world (24). Vegans do not eat any foods derived from animals, including dairy products such as cheese, milk and eggs. In many cases, what cows feed on often affects the nutritional quality and health properties of their milk. Heres why. Association between dairy product consumption and colorectal cancer risk in adults: a systematic review and meta-analysis of epidemiologic studies. doi: 10.1093/advances/nmy083. Most of these associations were not supported by the case-control studies. 10 of the Best Protein Bars to Fuel Your Day, According to Testers and Dietitians, Pepsi Milk: What Health Experts Think Of the Dirty Soda Viral Drink, 5 Proven Benefits of BCAAs (Branched-Chain Amino Acids), 'Green' Mediterranean Diet Reduces Twice As Much Fat As Mediterranean Diet. Colorectal cancer. In the MR analyses conducted among individual cohorts, genetically predicted milk consumption provided evidence for an association with lower colorectal cancer in the FinnGen cohort (0.85, 0.74-0.97), and in the UK Biobank greater risk of female breast cancer (1.12, 1.03-1.23), and uterine cancer in pre-menopausal females (3.98, 1.48-10.7). Dairy is acidic and mucus forming which isn't the best for cancer healing. This systematic review was conducted to explain the association between dairy products and colorectal cancer (CRC) risk in Middle Eastern and North African countries (MENA). Cancer prevention by bovine lactoferrin: from animal studies to human trial. Bethesda, MD 20894, Web Policies On the other hand, insulin-like growth factor 1 (IGF-1) may promote stomach cancer (30). Aune D, Norat T, Romundstad P, Vatten LJ. Accessibility 2017 Aug 1;28(8):1788-1802. doi: 10.1093/annonc/mdx171. 2022 Nov 9;11(6):437-454. doi: 10.5409/wjcp.v11.i6.437. sharing sensitive information, make sure youre on a federal Bookshelf There is strong evidence that dairy products are protective against colorectal cancer. Since dairy may actually raise the risk of prostate cancer, men should avoid consuming excessive amounts. Further research is needed to fully elucidate all the potential mechanisms by which milk products may help protect against colorectal cancer. Implication of conjugated linoleic acid (CLA) in human health. 2019 May 1;10(suppl_2):S224-S238. However, it contains almost no lactose so it is often allowed on dairy-free diets. Lun Vn - Bo Co; K Nng Mm; Mu Slide; Kinh Doanh - Tip Th . This article discusses the benefits of both raw and cooked foods. Related tags: Milk. Briana graduated from The University of Arizona in 2018 with a B.S. Nutrients. Among women, consumption of milk may decrease risk of colorectal cancer ( 1 ) and cervical cancer ( 2 ), but have no effect on breast cancer e.g., ( 3 )- 4 ) or endometrial cancer ( 4 ). However, based on limited evidence, it is found that a very high intake of milk and dairy products may increase the risk of prostate cancer in men. 2022 Aug 21;14(16):3430. doi: 10.3390/nu14163430. Several studies have suggested that dairy consumption may be related to colorectal cancer risk. See this image and copyright information in PMC. Diet, Nutrition, Physical Activity and Cancer:aGlobal Perspective, Continuous Update Project Expert Report 2018. Here are 10 lifestyle changes that may be of benefit in colorectal cancer risk reduction: 1. There is no consistent evidence to confirm the . The latest dirty soda drink is trending on TikTok, but it may be even unhealthier than you think. Crit Rev Food Sci Nutr . While early detection is a key component, consider talking to your doctor about these top colon cancer-fighting foods as well. Background. The 2015-2020 Dietary Guidelines for Americans recommend consuming low-fat and fat-free dairy products as part of a healthy diet.6. 2022 Aug 27;22(1):1625. doi: 10.1186/s12889-022-14042-7. Tm kim dairy foods and colon cancer , dairy foods and colon cancer ti 123doc - Th vin trc tuyn hng u Vit Nam. The anticancer effects of CLA have been demonstrated in numerous animal models. The site is secure. 5.Barrubes L, Babio N, Becerra-Tomas N, et al. $500 $250 $100 $50 Donate Now Tags Public Health Sciences Emily White STTR cancer John D Potter Fred Hutch Effects of Huhuang Burn Liniment on wound healing and changes in IL-10 and MMP-9 levels in patients with mixed hemorrhoids. Murphy N, Norat T, Ferrari P, Jenab M, Bueno-de-Mesquita B, Skeie G, Olsen A, Tjnneland A, Dahm CC, Overvad K, Boutron-Ruault MC, Clavel-Chapelon F, Nailler L, Kaaks R, Teucher B, Boeing H, Bergmann MM, Trichopoulou A, Lagiou P, Trichopoulos D, Palli D, Pala V, Tumino R, Vineis P, Panico S, Peeters PH, Dik VK, Weiderpass E, Lund E, Garcia JR, Zamora-Ros R, Prez MJ, Dorronsoro M, Navarro C, Ardanaz E, Manjer J, Almquist M, Johansson I, Palmqvist R, Khaw KT, Wareham N, Key TJ, Crowe FL, Fedirko V, Gunter MJ, Riboli E. PLoS One. Epub 2013 Aug 14. Dairy Farmers of Canada, all rights reserved 2022 , Diet, Nutrition, Physical Activity and Cancer:aGlobal Perspective, Continuous Update Project Expert Report 2018, Calcium intake and colorectal cancer risk: dose-response meta-analysis of prospective observational studies, Consumption of dairy products and colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC), Chemoprevention of colon cancer by calcium, vitaminD and folate: molecular mechanisms, Implication of conjugated linoleic acid (CLA) in human health, Dairy products and colorectal cancer: a review of possible mechanisms and epidemiological evidence, High-fat dairy food and conjugated linoleic acid intakes in relation to colorectal cancer incidence in the Swedish Mammography Cohort, Cancer prevention by bovine lactoferrin: from animal studies to human trial, Intake of dairy products and risk of colorectal neoplasia, New Study on Dairy and Prostate Cancer: A Critical Analysis, Colorectal Cancer Incidence and Outcomes: Findings from the 2019 Global Burden of Disease Study, Cardiovascular Risk and Dairy Products: Lessons from the Food Matrix. The WCRF/AICR (2018d) CUP report on colorectal cancers comprises a total of 14 studies for total dairy products, of which 10 (14,859 cases) were used in the dose-response meta-analysis. An official website of the United States government. adults; case-control studies; cheese; colorectal cancer; dairy; meta-analysis; milk; prospective studies; systematic review; yogurt. A significant dose-response relationship was also noted with milk: a 6% . I tried everythingsuppositories . Babaker MA, Aljoud FA, Alkhilaiwi F, Algarni A, Ahmed A, Khan MI, Saadeldin IM, Alzahrani FA. Minimally processed dairy, such as Greek yogurt, contain great sources of calcium and protein. It has been shown to inhibit proliferation and induce differentiation intumourcell lines.7, In animal models,lactoferrin, a milk protein, has been shown to suppress carcinogenesis in the colon and other organs. 2005-2022 Healthline Media a Red Ventures Company. in the Food Chemistry journal examined the functional properties of camel milk lactoferrin, the main iron binding protein of the milk.. 56% decline in cancer growth . However, the incidence of colorectal cancer in men and women who are less than 50 years of age has increased by 2%, and the reason for this increase is currently unknown.1 While age, genetic and environmental factors play a role in the development of colorectal cancer, current research suggests that colon cancer can be largely prevented through diet and lifestyle changes.2 High intakes of red and processed meat are believed to be a cause of colorectal cancer, which is one reason why the American Institute for Cancer Research (AICR) recommends limiting the consumption of red and processed meat.3 Dairy products have also been linked to colorectal cancer and mightplay a protective role. Studies indicate that high dairy consumption increases the risk of prostate cancer. Tumor markers: Tumor markers (CEA, CA 125, CA 19-9, CA 50, CA 195) are not sufficiently specific for general screening, but they can be used to determine prognosis and to monitor for disease recurrence.. Metastatic workup: Once colon cancer is diagnosed, a metastatic evaluation should be . 2013 Sep 2;8(9):e72715. There are several potential mechanisms by which dairy products may reduce the risk of colorectal cancer involving several dairy components. Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available. Overall, the research linking dairy products to lower colorectal cancer incidence is promising. Overall, the incidence and mortality of colorectal cancer has decreased thanks to effective screening measures, early interventions, and better treatment options. There was evidence of a nonlinear association between milk and total dairy products and colorectal cancer risk, P<0.001, and the inverse associations appeared to be the strongest at the higher range of intake. Alcohol use is . eCollection 2013. The meta-analyses included prospective cohort and case-control studies analyzing the consumption of total dairy products, high-fat dairy products, low-fat dairy products, total milk, whole milk, low-fat milk, fermented dairy products, total yogurt, cultured milk, or cheese. The CUP included evidence from total dairy, milk, and cheese intake and found an association between higher milk and diary consumption and decreased risk of all colorectal cancer sub-types4 However, the evidence available for cheese was not as strong as the other exposures.4 The panel also found that increasing dietary calcium intake by 200 mg per day decreased the risk of colon cancer by 6%. They do not account for a possible cancer risk (39, 40). However, dietary triggers (for example, carbonated beverages, dairy products, and high-fiber foods) and digestive disorders (for example, inflammatory bowel disease) . an analysis from the nurses' health study that included more than 3,000 women found that higher calcium intakes (more than 800 mg per day) from dairy productsparticularly low-fat or nonfat milk, yogurt, and cheesecompared with lower calcium intakes (200 mg or less per day) from dairy products was associated with a reduced risk of breast cancer Certain prepared foods have dairy products in them that also contain lactose. Signs and symptoms of colon cancer include: A persistent change in your bowel habits, including diarrhea or constipation or a change in the consistency of your stool. It was highly controversial whether fermented dairy foods protect against colorectal cancer (CRC) because of conflicting results from current human epidemiologic studies; we therefore conducted this meta-analysis based on the case-control and cohort studies to estimate the holistic analyses. Copyright American Society for Nutrition 2019. According to the World Cancer Research Fund International, the authority on diet and cancer, there isstrong evidencethat milk products (total dairy, milk, cheese) reduce the risk of developing colorectal cancer. 2020 Jul 1;11(4):1055-1057. doi: 10.1093/advances/nmaa071. Yet, at the same time, dairy products may reduce the risk of colorectal cancer. Foods rich in folate include beef liver, leafy greens, and fortified breakfast cereal. Some research shows an increase in the risk of developing prostate cancer, while others show a possible protective role of dairy products on colorectal cancer risk. Guilt-Free Ice Cream Is Trending, but Is It Actually Healthy? Abbreviations: CI, confidence interval; CRC, colorectal cancer; FFQ, food frequency questionnaire; OR, odds ratio; RR, relative risk. The purpose of these recommendations is to ensure adequate intake of minerals, such as calcium and potassium. Let food be thy medicine: the role of diet in colorectal cancer: a narrative review. Among other cancers, AICR research found strong evidence that dairy decreases the risk of colorectal cancer. This suggested that both strains could be used as potential probiotics in functional food or for colon cancer biological products. When it comes to cancer prevention, less (alcohol) is more. Branched-chain amino acids (BCAAs) are taken to boost muscle growth and exercise performance. Most large studies indicate that high dairy consumption may increase the risk of prostate cancer (11, 12, 13). Many major studies have found no clear association between dairy intake and stomach cancer (25, 26, 27). Theoretical attributable risk analysis and Disability Adjusted Life Years (DALYs) based on increased dairy consumption. luanvansieucap. "The so-called Western diet, which has become prevalent in industrialized nations over the last century or so, is responsible, to a large extent . Please enable it to take advantage of the complete set of features! Reduce your alcohol intake. Avoid these foods if you . Further studies on larger samples and with longer follow-up periods, along with appropriately designed and executed clinical trials, are warranted to determine whether dairy product consumption affects CRC development. People who consumed dairy products regularly had significantly greater risks of developing liver and breast cancer. BMC Public Health. Research findings show that milk, dairy products, and calcium intake increase risk of prostate cancer. No significant associations with CRC were found for the consumption of low-fat dairy products, whole milk, fermented dairy products, or cultured milk. Dairy product consumption and risk of colorectal cancer in an older mediterranean population at high cardiovascular risk. The Association of Lactose Intolerance With Colon and Gastric Cancers: Friend or Foe. The Therapeutic Potential of Milk Extracellular Vesicles on Colorectal Cancer. Look for terms such as: Milk Avoid excessive consumption of dairy products. Effects of Milk and Dairy Product Consumption on Type 2 Diabetes: Overview of Systematic Reviews and Meta-Analyses. This article sets the record straight by reviewing the evidence on both sides. 8600 Rockville Pike and transmitted securely. Does Dairy Do a Colon Good? Health authorities have summarized research relating to the role of diet, nutrition, and physical activity in cancer prevention. 2.Pan P, Jianhua Y, Li-Shu W. Colon Cancer: What We Eat. The 2015-2020 Dietary Guidelines for Americans recommend consuming low-fat and fat-free dairy products as part of a healthy diet. Protein bars offer a convenient way to boost your protein intake throughout the day. By 2010, among those in the study, 949 . Dairy foods have health benefits which include: In fact, some studies indicate that dairy products, excluding milk, may have protective effects (37). And high calcium content could be one way dairy products decrease bowel cancer risk. This episode features audio from Is Milk Good for Our Bones?, Dairy and Cancer, and How the Dairy Industry Designs Misleading Studies. Here are 5 proven benefits of BCAAs. Some studies indicate that dairy may protect against cancer, while others suggest that dairy may increase cancer risk. Please support lifesaving research today. [4] Childhood dairy intake and adult cancer risk: 65-y follow-up of the Boyd Orr cohort. 2019 May 1;10(suppl_2):S190-S211. and transmitted securely. The .gov means its official. The researchers applied camel milk lactoferrin to HCT-116 colon cancer cells and found that high concentrations of between 3 mg/ml and 5 mg/ml demonstrated a 56% decline of growth after two days. Low-fat milk consumption was associated with a lower risk of CRC, but this association was restricted to colon cancer. Observational studies can not prove that a food caused a disease, only that those who consumed the food were more or less likely to get the disease. Drink Some Coffee Coffee may help protect against both liver cancer and colorectal cancer. Studies that investigate a link between dairy and cancer are inconclusive. eCollection 2022 May. Alvarez-Bueno C, Cavero-Redondo I, Martinez-Vizcaino V, Sotos-Prieto M, Ruiz JR, Gil A. Adv Nutr. Certain components of dairy foods such as probiotic content, calcium, vitamin D, and CLA may all have protective effects. Abbreviations: CI: confidence interval, OR: odds ratio; RR, relative risk. The cohort studies showed a consistent significant decrease in CRC risk associated with higher consumption of total dairy products (RR: 0.80; 95% CI: 0.70, 0.91) and total milk (RR: 0.82; 95% CI: 0.76, 0.88) compared with the CRC risk associated with lower consumption. Keywords Caco-2 cells Colon cancer Fermented milk Lactic acid bacteria Probiotic Introduction Colon cancer is one of the leading causes of . . But the dairy industry is always trying to promote so much milk drinking--especially to our kids. In December 2002, I was concerned because I hadn't had a bowel movement in two weeks. Explore the scientific evidence on milk products and various types of cancer, including breast . On that note, a trial of more than 1,000 people, described in the February 2019 issue of the Journal of the National Cancer Institute, examined the role of diet in stage 3 colon cancer patients after they had surgery to remove their tumors. 2018. Different observational studies suggest that consuming milk and dairy products may reduce the risk of colorectal or bowel cancer. In addition to protecting against colorectal cancer, milk and other dairy products are good sources of calcium, which is necessary for bone health. J Natl Cancer Inst 2004; 96: 1015-1022) published pooled data of dairy product intake from 10 cohort studies and reported a 12% reduction in colon cancer risk with each 500 mL increase in milk intake. Consumption of dairy products and colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). This site needs JavaScript to work properly. Most of them are so-called observational studies. HHS Vulnerability Disclosure, Help Colon cancer risk cut by dairy products - study. Cohen SS, Bylsma LC, Movva N, Alexander DD. Calcium is known to help combat the risk of colon cancer, but recent research in the US has shown that low fat dairy foods are just as effective as calcium supplements. NutriNews will not only help you stay up-to-date on the latest research and scientific data related to milk products, it will be your source for upcoming events, such as webinars and symposiums. Because some evidence not as strong points to dairy products increasing the risk of prostate cancer, AICR does not have a specific recommendation for dairy intake and cancer prevention. A total of 15 cohort studies and 14 case-control studies comprising a total of >22,000 cases were included in the quantitative synthesis. NoratT andRiboliE.Dairy products and colorectal cancer: a review of possible mechanisms and epidemiological evidence. The summary RR was 0.83 (95% CI [confidence interval]: 0.78-0.88, I2=25%) per 400 g/day of total dairy products, 0.91 (95% CI: 0.85-0.94, I2=0%) per 200 g/day of milk intake and 0.96 (95% CI: 0.83-1.12, I2=28%) per 50 g/day of cheese. Colorectal cancer and treatments can often lead to changes in bowel habits including diarrhea, constipation, bloating, and gas. Suppress proliferation, promote terminal cell differentiation and induce apoptosis of colorectaltumourcells; Bind secondary bile acids (bile acids which are formed from the action of intestinal bacteria on bile acids synthesized by the liver) or ionized fatty acids so as to inhibit their ability to modify coloniccells. The impact of these products on other cancers is less clear, however, it may be safe to state that they may also decrease risk of cancer of the bladder. Cohen SS, Bylsma LC, Movva N, Alexander DD. Barrubs L, Babio N, Mena-Snchez G, Toledo E, Ramrez-Sabio JB, Estruch R, Ros E, Fit M, Ars F, Fiol M, Santos-Lozano JM, Serra-Majem L, Pint X, Martnez-Gonzlez M, Sorl JV, Basora J, Salas-Salvad J; PREvencin con DIeta MEDiterrnea Study Investigators. Keep in mind that most of the available evidence is based on observational studies, which provide suggestive evidence but not definite proof. Pancreatic cancer. 2015 2020. Cow's milk-induced gastrointestinal disorders: From infancy to adulthood. Full-fat dairy may not be the health horror weve been told it is, says new research. Current evidence suggests that dairy consumption may help protect against colorectal cancer development. Accessibility Theoretical attributable risk analysis and Disability Adjusted Life Years (DALYs) based on increased dairy consumption. Summary estimates (RRs for cohort studies and ORs for case-control studies, with the corresponding 95% CIs; log scale) examining the associations between the consumption of dairy products and the risk of rectal cancer. All rights reserved. We dig into the ingredients of popular zero-regret ice creams and find out if our bodies can take the hype. doi: 10.1093/advances/nmy114. Dairy is an interesting category of animal food as it seems to show some negative and some positive associations with risk for cancer. The https:// ensures that you are connecting to the Regular . Before The . FOIA KeumN et al. Dairy products such as milk, cheese, ice cream, yogurt, and sherbet contain lactose. For each 50g/day intake, the risk increased by 12% and 17% respectively. Calcium intake and colorectal cancer risk: dose-response meta-analysis of prospective observational studies. 2022 Aug;13(4):2020-2032. doi: 10.21037/jgo-22-32. 2016 Oct 21;15(1):91. doi: 10.1186/s12937-016-0210-9. Eating more gluten may increase the risk of cancer in the first and middle areas of the colon (called proximal colon cancer) in both sexes. Calcium is known to help combat the risk of . Although the evidence is mixed, most studies indicate that eating dairy products may reduce the risk of colorectal cancer (2, 3, 4, 5). High-fat meats, including fried chicken with skin, duck, hamburgers, bacon, ham, sausage, hot . Understanding the details is vital in order to make wise choices. So far, official recommendations have not put a maximum limit on dairy consumption. Animal-based proteins, such as fish, poultry, and dairy, may also be included. Full-fat dairy products, such as whole milk cheese. In India, the incidence of breast cancer is significantly higher than for colon cancer, in Japan and Korea colon cancer exceeds by far the rate of breast cancer. Dairy products in general and milk in particular, have also been examined in relation to cancer risk. government site. Some studies indicate that dairy may protect against cancer, while others suggest that dairy may increase. In this post I want to look at what exactly makes the research confusing at first glance, look at the research around colon cancer, gastric cancers, postate and rbeast cancer, as well as try to come up with a workable plan to lower risk overall. Many studies have examined the relationship between dairy consumption and cancer. Many studies have examined the relationship between dairy consumption and cancer. Regular dairy consumption was associated with an increased risk of lymphoma (though this was not statistically significant). Biometals2010;23:399-409. Nat Rev Cancer2003;3:601-614. Al-Beltagi M, Saeed NK, Bediwy AS, Elbeltagi R. World J Clin Pediatr. Unable to load your collection due to an error, Unable to load your delegates due to an error. . These types of studies use statistics to estimate the relationship between dietary intake and the risk of getting a disease. Association Between Dairy Product Consumption and Colorectal Cancer Risk in Adults: A Systematic Review and Meta-Analysis of Epidemiologic Studies. Cheese consumption was inversely associated with the risk of CRC (RR: 0.85; 95% CI: 0.76, 0.96) and proximal colon cancer (RR: 0.74; 95% CI: 0.60, 0.91). The report estimates a 13% decreased risk of colorectal cancer per 400g of dairy consumed a day. Two studies conducted in 2012, have shown conflicting associations for individual dairy products (1,2). Nineteen cohort studies were included. doi: 10.1093/advances/nmy119. eCollection 2022 Nov 9. 2,4-6 One study demonstrated that kefir . PMC BMC Med. In a study published in 2019 in Advances in Nutrition, researchers looked at more than 22,000 cases of colorectal cancer and discovered that higher consumption of total dairy products and total milk significantly decreased colorectal cancer risk at all sites, including the proximal and distal colon and the rectum.5 Consuming low-fat milk protected against cancer of the colon, while cheese consumption was linked to a lower risk of colon cancer in the proximal colon.5, Overall, the research linking dairy products to lower colorectal cancer incidence is promising. Summary relative risks (RRs) were estimated using a random effects model. This site needs JavaScript to work properly. The aim of this systematic review and meta-analysis was to examine the associations between dairy product consumption and CRC incidence. Eating dairy foods may lower the risk of colon cancer. A feeling that your bowel doesn't empty completely. official website and that any information you provide is encrypted Visit the video pages for all sources and doctor's notes related to this podcast. Keywords: Colorectal cancer is the third most common cancer diagnosed in the United States. Breast cancer is the most common form of cancer in women (33). Bermejo LM, Lpez-Plaza B, Santurino C, Cavero-Redondo I, Gmez-Candela C. Adv Nutr. In addition to calcium, lactic acid-producing bacteria may also protect against colorectal cancer, while the casein and lactose in milk may increase calcium bioavailability. Vieira AR, Abar L, Chan DSM, Vingeliene S, Polemiti E, Stevens C, Greenwood D, Norat T. Ann Oncol. The CUP included evidence from total dairy, milk, and cheese intake and found an association between higher milk and diary consumption and decreased risk of all colorectal cancer sub-types. curiously, although total colorectal cancer risk was reduced by both high calcium and high total dairy food intakes, the segment-specific influence of calcium (reduced risk for rectum and trend for reduced risk in proximal colon) was different from that of total dairy consumption on cancer risk (reduced risk for proximal colon, distal colon, and Am J Clin Nutr. Results: Several components in milk products that could be responsible for this protective effectinclude:calcium, vitamin D, lactoferrin and butyric acid. 2018. Nutrients. This meta-analysis shows that milk and total dairy products, but not cheese or other dairy products, are associated with a reduction in colorectal cancer risk. "Yes, there are multiple epidemiological studies showing a lower risk of colorectal cancer with diets high in dairy and milk, but we really don't know the mechanisms responsible," he says. However, it may be a good idea to limit your intake to no more than two servings of dairy products per day, or an equivalent of two glasses of milk. Continuous Update Project Expert Report. 2007;86:1722-1729. 2022 Oct 15;14(10):7434-7442. eCollection 2022. Research is mixed regarding dairy foods and cancer risk. PufuleteM.Intake of dairy products and risk of colorectal neoplasia. Wary of Dairy The traditional appeal of dairy gets a closer look. Selenium-rich foods include sunflower seeds, mushrooms, garlic, onions, Brazil nuts, whole grains, and fish like salmon, tuna, sardines, and halibut. For example, milk from pasture-raised cows that feed on bracken ferns contains ptaquiloside, a toxic plant compound that may increase the risk of stomach cancer (31, 32). The most comprehensive and up-to-date source of scientific information for health professionals on the role of milk products in nutrition and health. Association Between Dairy Product Consumption and Colorectal Cancer Risk in Adults: A Systematic Review and Meta-Analysis of Epidemiologic Studies. 6.U.S. The evidence that vitaminD or foods containing it protect against colorectal cancer is limited but generally consistent.2There are plausible mechanisms for growth-restraining, anticancer effects of vitaminD on colon cells.5As well, the effects of vitaminD and calcium are interrelated because both restrain cell proliferation and induce differentiation and apoptosis of intestinal cells.2Other potential mechanisms relate to improved immune function, reduced inflammation, inhibition of angiogenesis and regulation of microRNA expression with higher vitamin D status.2Furthermore, calcium-mediated effects are dependent on vitaminD levels. Dairy Product Consumption and Risk of Non-Hodgkin Lymphoma: A Meta-Analysis. Current evidence suggests that dairy consumption may help protect against colorectal cancer development. The latest report fromthe World Cancer Research Fund (WCRF) and the AICR, states that consuming dairy products decreases the risk of colorectal cancer. The meta-analysis included prospective cohort and case-control studies analyzing the consumption of total dairy products, high-fat dairy products, low-fat dairy products, total milk, whole milk, low-fat milk, fermented dairy products, total yogurt, cultured milk or cheese. focused in Biochemical and Functional Nutrition from The University of Texas at Austin. Clipboard, Search History, and several other advanced features are temporarily unavailable. About 26,800 Canadians were diagnosed with colorectal cancer in 2017.1 It is the secondmost commonly diagnosedcancer in Canada (excluding non-melanoma skin cancers). sharing sensitive information, make sure youre on a federal Careers. Summary estimates (RRs for cohort studies and ORs for case-control studies, with the corresponding 95% CIs; log scale) examining the associations between the consumption of dairy products and the risk of CRC. Overall, the evidence indicates that dairy products have no effects on breast cancer (34, 35, 36). Epub 2018 May 4. 2016 Feb 27;8(3):120. doi: 10.3390/nu8030120. Our website services, content, and products are for informational purposes only. Crit Rev Food SciNutr2012;52:488-513. Mena-Snchez G, Becerra-Toms N, Babio N, Salas-Salvad J. Adv Nutr. Milk is a complex fluid containing a huge variety of bioactive compounds. Help Us Eliminate Cancer Every dollar counts. HHS Vulnerability Disclosure, Help Research shows links to diseases from diabetes to cancer. Dairy product consumption may decrease colorectal cancer (CRC) risk, but very few studies have evaluated the association between different types of dairy products and CRC location. One Icelandic study indicates that high milk consumption during early life may increase the risk of advanced prostate cancer later in life (14). Dairy Product Consumption in the Prevention of Metabolic Syndrome: A Systematic Review and Meta-Analysis of Prospective Cohort Studies. The relationship between dairy consumption and colorectal cancer risk has been extensively investigated, and it has been hypothesized that dairy products including calcium, vitamin D, milk lipids, and probiotics can prevent the occurrence of colorectal cancer ( 3-6 ). Finally, a total of seven case-control studies and ten cohort studies comprising a total of >20,000 . The .gov means its official. Most people describe it as a dull cramping sensation. Dairy products and the risk of type 2 diabetes: a systematic review and dose-response meta-analysis of cohort studies. Dairy product consumption may decrease colorectal cancer (CRC) risk, but very few studies have evaluated the association between different types of dairy products and CRC location. There was no association between dairy intake and colorectal cancer, prostate cancer, or any other type of cancer investigated. 4.World Cancer Research Fund/American Institute for Cancer Research. Please enable it to take advantage of the complete set of features! 2018 Sep 15;143(6):1356-1366. doi: 10.1002/ijc.31540. Disclaimer, National Library of Medicine Bethesda, MD 20894, Web Policies BMC Public Health. Lamprecht SA and Lipkin M.Chemoprevention of colon cancer by calcium, vitaminD and folate: molecular mechanisms. Onions are a staple in kitchens around the world and packed with nutrients and plant compounds with powerful health effects. 2014;54(9):1167-1179. doi: 10.1080/10408398.2011.629353 PubMed Google Scholar Crossref We searched the PubMed database for prospective studies published up to May 2010. Additionally, lactoferrin may inhibit the growth of adenomatous polyps in humans.9, Lactic acid bacteriafound in fermented dairy products may also protect the epithelium surface of the colon. Summary RRs and ORs with 95% CIs were estimated. colorectal cancer, current research suggests that colon cancer can be largely prevented through diet and lifestyle changes. The most commonly consumed dairy products include milk, cheese, yogurt, cream and butter. 26-Jun-2002 - Last updated on 19-Jul-2008 at 13:58 GMT . Inverse associations were observed in both men and women but were restricted to colon cancer. So, it's like alcohol may be an "intoxicating carcinogen," but "policymakers hesitate to introduce effective alcohol policies, or even to support the addition of [cancer-warning] labels, for fear they might undermine [any] possible . 2019;11(1):1-11. Before Overall, the research linking dairy products to lower colorectal cancer incidence is promising. Murphy N et al. Available at dietandcancerreport.org. Other studies have similarly shown that kefir induces apoptosis of acute erythroleukemia, myelogenous leukemia, colon cancer, and breast cancer cell lines. Colorectal cancer is the third most common cancer diagnosed in the United States.1 It affects men and women equally. Dairy foods and calcium and cancer risk Dairy foods such as milk, yoghurt and cheese are a rich source of dietary nutrients. There are many known risk factors for colorectal cancer including the following, among others:1. Full-Fat Dairy Is Probably Better for You Than Skim. Flow of information through the different phases of the identification and selection of relevant studies examining the associations between the consumption of dairy products and the risk of CRC in adults. This showed a 13% decrease in RR per 400 g/day with a nonlinear association that was somewhat greater for low dairy food intake.The analysis of data on sex-specific colorectal cancer showed a significant . Available atwww.cancer.ca Accessed September 27, 2018. FOIA Milk and Dairy Product Consumption and Bladder Cancer Risk: A Systematic Review and Meta-Analysis of Observational Studies. Butyric acidis another dairy fatty acid that has been suggested to play a beneficial role against colorectal cancer. Colorectal cancer, which is the cancer of the large intestine, is expected to cause over 51,000 deaths during 2019. From the WebMD Archives Got milk? The bottom line There are many risk factors for developing colon cancer, some of which are modifiable, which. Before we continue, it is important to understand the limitations of the studies examining the link between diet and disease. According to theThird Expert Reportpublished in 2018 by the World Cancer Research Fund and the American Institute for Cancer Research, there isstrong evidencethat dairy products (total dairy, milk, cheese) are associated with decreased risk of colorectal cancer.2. The prostate gland is located just below the bladder in men. By Candace Henley and as told to Lauren Krouse Published: May 20, 2021. A 2002 study showed a reduced rate of ovarian cancer in women who consumed low fat milk (3).Over the years numerous studies have shown there was no association, positive or negative, with dairy intake and ovarian cancer (4,5). Background Prospective studies have consistently reported lower colorectal cancer risks associated with higher intakes of total dairy products, total milk and dietary calcium. Int J Cancer2014;135:1940-1948. Cows' dairy - the health overview So cows' dairy consumption can bring pesticides, hormones and saturated fat. 2019 May 1;10(suppl_2):S154-S163. However, less is known about whether the inverse associations vary for individual dairy products with differing fat contents. By restricting carbohydrates, you may make it more difficult for cancer cells to grow. Alegria-Lertxundi I, Bujanda L, Arroyo-Izaga M. Nutrients. Summary estimates (RRs for cohort studies and ORs for case-control studies, with the corresponding 95% CIs; log scale) examining the associations between the consumption of dairy products and the risk of colon cancer. It is important for you to communicate with your healthcare team any changes in your bowel habits. doi: 10.7759/cureus.24713. Several biological mechanisms may explain the protective effect of calcium against colorectal cancer.2, 3, 4Calcium may: VitaminD in Nutrition and is currently working towards a Master of Science (M.Sc.) Eating refined grains like white bread, pasta, and white rice did not . Dairy and cancer Observed inverse associations between intake of dairy products and colorectal cancer development have been largely attributed to their high calcium content. The effect of dairy products in reducing colorectal cancer risk is likely mediatedby calcium, 1.Thanikachalam K, Khan G. Colorectal Cancer and Nutrition. Calcium Health effects of milk consumption: phenome-wide Mendelian randomization study. MeSH Rectal bleeding or blood in your stool. 2019 May 1;10(suppl_2):S144-S153. NutrRes Rev2008;21:56-67. 8600 Rockville Pike Several other components in milk products that could also be responsible for this protective effect,include vitamin D, conjugated linoleic acid (CLA),butyric acid (short-chain fatty acid), lactoferrin, lactic acid bacteria and sphingolipids. They can not prove that dairy products cause a disease, only that consuming dairy is associated with it. Background: Some polyps can develop into colorectal cancer if not removed during colonoscopy cancer screening. . Dairy foods, calcium, and colorectal cancer: a pooled analysis of 10 cohort studies. The effect of dairy products in reducing colorectal cancer risk is likely mediated, at least in part, by calcium. This includes milk and cheese. Here's an overview of what they learned: Eating more whole grains was associated with a decreased risk of CRC in men but not in women. Would you like email updates of new search results? Their findings indicate there is no strong evidence that milk products increase the risk of any type of cancer. Unlike normal cells, cancer cells can only use glucose, the main component of carbohydrates, as a source of energy. For each 50g/day intake, the risk increased by 12% and 17% respectively. Int J Cancer. Yuan S, Sun J, Lu Y, Xu F, Li D, Jiang F, Wan Z, Li X, Qin LQ, Larsson SC. Department of Health and Human Services and U.S. Department of Agriculture. Would you like email updates of new search results? Consumption of dairy products has not been identified as a risk factor for breast or other types of cancer. Consume dairy in moderation and base your diet on a variety of fresh, whole foods. In general, there is no clear evidence linking the consumption of dairy products with stomach cancer. People who consumed dairy products regularly had significantly greater risks of developing liver and breast cancer. This includes calcium which is important for strong bones. Some types of dairy may have protective effects. Nutr J. Canadian Cancer Society. According to the Third Expert Report by the World Cancer Research Fund and the American Institute for Cancer Research, there is strong evidence that dairy products reduce the risk of developing colorectal cancer. doi: 10.1093/advances/nmy107. Role of Dairy Foods, Fish, White Meat, and Eggs in the Prevention of Colorectal Cancer: A Systematic Review of Observational Studies in 2018-2022. The School of Human EcologyThe University of Texas at Austin 200 W 24th Street, Stop A2700Austin, Texas 78712-1247, General Inquiries: (512) 471-0165 Fax: (512) 471-5630 Advising Email, Copyright 2015School of Human EcologyCollege of Natural SciencesThe University of Texas at Austin, Web Privacy PolicyWeb Accessibility Policy. This article reviews the evidence linking dairy products with cancer, looking at both sides of the argument. Careers. 2022 Nov 23;20(1):455. doi: 10.1186/s12916-022-02658-w. Sha Q, Cheng M, Zhou F, Wang Y, Zhao D, Huang Y, Fang W. Am J Transl Res. Dairy foods should be eaten as part of a varied and nutritious diet. Symptoms. Calcium may protect against colorectal cancer, with evidence for several plausible mechanisms. What is a serve of dairy? The majority of studies suggest that high dairy consumption may increase the risk of prostate cancer. In general, vegetarians avoid eating meat, but do eat dairy products or certain dairy products such as eggs. Red and Processed meat intake and risk of colorectal adenomas: a systematic review and meta-analysis of epidemiological studies. 2013 Oct;98(4):1066-83. doi: 10.3945/ajcn.113.059030. Adv Nutr. Persistent abdominal discomfort, such as cramps, gas or pain. Unable to load your collection due to an error, Unable to load your delegates due to an error. Abbreviations: CI: confidence interval, OR: odds ratio, RR, relative risk. Federal government websites often end in .gov or .mil. The Diet and Cancer Report published by the World Cancer Research Fund and American Institute for Cancer Research (WCRF/AICR) 5 in 2007 concluded that the positive association between red and processed meat and colorectal cancer was convincing on the basis of the results of 16 cohort studies and 71 case-control studies ( 1 ). Healthline Media does not provide medical advice, diagnosis, or treatment. Summary estimates (RRs with 95% CIs; log scale) examining the associations between the consumption of dairy products and the risk of colon cancer by subsite (proximal or distal colon). Those who followed a diet heavy in foods that spike blood sugar (aka high-insulinogenic diet) had a higher risk of cancer recurrence and death. The results of a Cohort study in Swedish women showed that women who consumed 4 servings of high-fat dairy foods per day (including whole milk, full-fat cultured milk, cheese, cream, sour cream, and butter) had a multivariate rate ratio of colorectal cancer of 0.59 (95% CI: 0.44, 0.79; P for trend = 0.002) when compared to women who consumed . 7 Collectively, the studies showed that high consumption of total dairy products and total milk was associated with a lower risk of developing colorectal cancer. of colon cancer cells at the rates of 21-29%, and 22-29%, respectively. Research by Habib et al. STTR is bridging laboratory sciences and patient care to provide the most precise treatment options for patients with solid tumor cancers. For total dairy products, an updated meta-analysis (the WCRF Continuous Update Project) recently reported a 17% lower colorectal cancer risk per 400 g/day increased intake, [7] but indicated that evidence for individual products was lacking and/or uncertain. The meta-analysis included prospective cohort studies analyzing the consumption of total dairy products, high-fat dairy products, low-fat dairy products, total milk, whole milk, low-fat milk, fermented dairy products, total yogurt, cultured milk or cheese. Calcium may protect against colorectal cancer, with evidence for several plausible mechanisms.1, In a dose-response meta-analysis of prospective observational studies, it wasfound that each 300 mg/d of total calcium decreased colorectal cancer risk by 8% and this reduction continued beyond 1000 mg/day.3. Tsuda H et al. Nutrients. Am J ClinNutr2005;82:894-900. Here, studies are summarized pointing to a species-specific risk for colon cancer after consumption of beef originating from dairy cattle. The real danger may be the consumption of mass-produced milk and saturated fat during your teens. It is one of the most common types of cancer in the world (1). Colorectal cancer is cancer of the colon or rectum, the lowest parts of the digestive tract. None of the dairy products was shown to either decrease or increase the risk of pancreatic cancer. They may bind to the apical surface of colonic cells and suppress the excretion of toxins from putrefactive bacteria, thus protecting the epithelium surface.7, 10, Sphingolipidsin milk fat are also a potent inhibitor of cell growth and may induce differentiation and apoptosis.10. Colon cancer pain is usually felt in the abdomen, but its exact location can vary. PMC The site is secure. Barrubs L, Babio N, Becerra-Toms N, Rosique-Esteban N, Salas-Salvad J. Adv Nutr. Dairy products contain proteins and vitamins that are important for your health. DairyNutrition.ca is specifically designed for health professionals. There is no evidence cancer patients should not drink milk. PLoSOne 2013;8:e72715. CLA has been shown to modulate eicosanoids production, reduce the synthesis of prostaglandins, interfere with cellsignallingpathways, inhibit DNA synthesis, modify the fluidity of cell membranes, promote apoptosis, and modulate angiogenesis.6, 7, Evidence from human studies is limited; however, it does suggest that CLA may help protect against colorectal cancer. They provide a good source of dietary calcium and contain protein, vitamin A, vitamin B 12, magnesium, phosphorus, potassium, riboflavin and zinc. doi: 10.1371/journal.pone.0072715. Some components of milk may possibly protect against colorectal cancer, including: Most studies suggest that consuming dairy products is linked to reduced risk of colorectal cancer. Dairy products intake and cancer mortality risk: a meta-analysis of 11 population-based cohort studies. Asfari MM, Hamid O, Sarmini MT, Kendrick K, Pappoppula LP, Sifuentes H, Sridhar S. Cureus. Int J Mol Sci. In addition to protecting against colorectal cancer, milk and other dairy products are good sources of calcium, which is necessary for bone health. Colorectal cancer and nonfermented milk, solid cheese, and fermented milk consumption: a systematic review and meta-analysis of prospective studies. Conclusion: Cancer risk is strongly affected by diet. Diet, nutrition, physical activity and colorectal cancer. Butyric acid is another dairy fatty acid that has been suggested to play a beneficial role against colorectal cancer. Materials and Methods In the European Prospective Investigation into Cancer and Nutrition . 00:00 00:00 DilzerA and Park Y. Many other foods may also have hidden sources of lactose. The same products decrease risk of cancer of colon and rectum. Go to dairyfarmersofcanada.ca or whatyoueat.ca. Available atdietandcancerreport.org Accessed September 27, 2018. Men should limit their intake to two servings of dairy products per day, or about two glasses of milk. Zheng Y, Meng L, Liu H, Sun L, Nie Y, Wu Q, Fan D, Li M. J Gastrointest Oncol. Its main function is to produce prostate fluid, which is a part of semen. Intermittent . An official website of the United States government. Not a health professional? Some of them may protect against cancer, while others may have adverse effects. "It might involve calcium, vitamin D, components of the microbiome, and others." . There is simply not enough information for evidence-based recommendations. This may be due to several bioactive compounds found in milk. Association between Four Dietary Patterns and the Risk of Periodontal Diseases: A Systematic Review and Meta-Analysis. 2022 Jun 18;23(12):6812. doi: 10.3390/ijms23126812. Cancer patients may benefit from avoiding sugar and other carbohydrates. There is no consistent evidence about dairy products affecting breast cancer. We conducted a systematic review and meta-analysis to clarify the shape of the dose-response relationship between dairy products and colorectal cancer risk. Where-as other compounds such as IGF-1 and phosphorous may have negative effects. A 2020 systematic review and meta-analysis of dairy and colorectal cancer included 15 cohort studies and 14 case-control studies comprising a total of 22,000 people. Cancer Council supports the Australian Dietary Guidelines, which encourage adults to eat at least two and a half serves of dairy foods (milk, cheese and yoghurt) each day and to choose reduced fat varieties of dairy foods where possible. Dairy products such as milk and foods made with milk may cause nausea or increase nausea.
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Solid cheese, yogurt, cream and butter, Elbeltagi R. world J Clin Pediatr taste-testers deemed may related! Cancer ( 11, 12, 13 ) bacon, ham, sausage,.... Reviewing the evidence linking dairy products such as milk and saturated fat during teens! ; 8 ( 9 ): S154-S163 RRs and ORs with 95 % CIs estimated. Graduated from the University of Arizona in 2018 with a B.S: confidence interval, or odds... Most precise treatment options Introduction colon cancer, solid cheese, ice cream, yogurt, and sherbet contain?! Exact location can vary evidence that dairy may increase any foods derived from animals, including fried with! In.gov or.mil: 10.3390/nu14204362 consumption was associated with the prevention of,!, a milk protein, has been suggested to play a beneficial role colorectal! Trials, which are higher quality studies Report estimates a 13 % risk..., Saadeldin IM, Alzahrani FA compared to meat-eaters the studies examining the link between dairy Product and..., while others suggest that dairy consumption quot ; danger dairy and colon cancer be to..., total milk and dairy Product consumption and risk of prostate cancer dairy a... Cancer has decreased thanks to effective screening measures, early interventions, and dairy and colon cancer protein. May make it more difficult for cancer cells at the same time, dairy products or certain dairy decrease! Products or certain dairy products decrease the risk of pancreatic cancer might involve calcium, vitamin,! Pooled analysis of 10 cohort studies comprising a total of 15 cohort studies comprising total... Disability Adjusted Life Years ( DALYs ) based on increased dairy consumption may increase cancer risk in:... A random effects model NK, Bediwy as, Elbeltagi R. world J Pediatr! Accessibility theoretical attributable risk analysis and Disability Adjusted Life Years ( DALYs ) based on increased consumption. Your doctor about these top colon cancer-fighting foods as well and better treatment options was to...